Description
Overview
Semax is a research-grade synthetic heptapeptide based on the ACTH(4–10) fragment (Met-Glu-His-Phe-Pro-Gly-Pro), a portion of adrenocorticotropic hormone that retains neurotrophic activity while lacking hormonal effects on the adrenal cortex. The Pro-Gly-Pro C-terminal modification provides enhanced stability against enzymatic degradation, making Semax a practical and reliable research tool for neuroscience investigations.
Published Research
Semax has been the subject of substantial preclinical research, with studies examining:
- BDNF, NGF, and GDNF neurotrophic factor expression in brain tissue models
- Cognitive performance and memory formation in rodent behavioral assays
- Neuroprotective mechanisms against oxidative stress in cell culture
- Dopaminergic and serotonergic system modulation in neurochemical studies
- Cerebral blood flow regulation and neurovascular coupling research
- Gene expression profiling in central nervous system tissue
- Immune system modulation and anti-inflammatory pathway activation
Specifications
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Molecular Weight: 813.93 g/mol
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
- Solubility: Soluble in bacteriostatic water or sterile water
- Storage: Store at -20°C for long-term stability. Reconstituted solutions should be refrigerated at 2–8°C
- CAS Number: 80714-61-0
Handling
This product is intended for laboratory research only. Reconstitute with bacteriostatic water for research applications. Use aseptic technique during preparation. Refer to published literature for appropriate research concentrations.
For research and laboratory use only. Not for human consumption. Sold exclusively to qualified researchers and licensed institutions.
