Description
Overview
Selank (TP-7) is a research-grade synthetic heptapeptide developed as a stabilized analog of the naturally occurring immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg). The addition of a Pro-Gly-Pro sequence to the C-terminus of tuftsin confers enhanced enzymatic stability, allowing for more consistent results in research protocols. Selank is of particular interest in neuroscience research due to its observed effects on multiple neurotransmitter systems in preclinical models.
Published Research
Selank has been studied extensively in preclinical research settings, with publications covering:
- Brain-derived neurotrophic factor (BDNF) expression modulation in animal models
- GABAergic system interactions and anxiolytic-like behavioral observations in rodent studies
- Serotonin and norepinephrine metabolism and monoamine system regulation
- Immunomodulatory activity including cytokine profile modulation
- Cognitive function and memory consolidation research in behavioral assays
- Enkephalin degradation enzyme inhibition studies
- Gene expression profiling showing effects on 36+ genes in hippocampal tissue
Specifications
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Molecular Weight: 751.9 g/mol
- Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
- Solubility: Soluble in bacteriostatic water or sterile water
- Storage: Store at -20°C for long-term stability. Reconstituted solutions should be refrigerated at 2–8°C
- CAS Number: 129954-34-3
Handling
This product is intended for laboratory research only. Reconstitute with bacteriostatic water for research applications. Use aseptic technique during preparation. Refer to published literature for appropriate research concentrations.
For research and laboratory use only. Not for human consumption. Sold exclusively to qualified researchers and licensed institutions.
