Description
Overview
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Complex) is a research-grade naturally occurring tripeptide with a high affinity for copper(II) ions. First identified in human plasma, GHK-Cu levels naturally decline with age, which has made it a subject of significant research interest. The copper-peptide complex has been shown to modulate the expression of a large number of genes in cell culture studies, making it a powerful research tool for investigating regenerative and remodeling pathways.
Published Research
GHK-Cu has a rich body of published research spanning multiple fields:
- Collagen I, III, and elastin synthesis stimulation in fibroblast cultures
- Antioxidant enzyme upregulation (SOD, catalase) and free radical reduction assays
- Extracellular matrix remodeling via metalloproteinase regulation
- Gene expression studies showing modulation of 4,000+ human genes
- Growth factor signaling (TGF-β, VEGF, FGF-2) in in-vitro models
- Stem cell differentiation and tissue regeneration research
- Anti-inflammatory cytokine modulation in cell culture assays
Specifications
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder (blue-colored due to copper complex)
- Molecular Weight: 403.93 g/mol
- Sequence: Gly-His-Lys:Cu(II)
- Solubility: Freely soluble in water
- Storage: Store at -20°C for long-term stability. Reconstituted solutions should be refrigerated at 2–8°C
- CAS Number: 49557-75-7
Handling
This product is intended for laboratory research only. Reconstitute with sterile water for research applications. Use aseptic technique during preparation. Refer to published literature for appropriate research concentrations.
For research and laboratory use only. Not for human consumption. Sold exclusively to qualified researchers and licensed institutions.
