Description
Overview
Tesamorelin is a research-grade synthetic analog of human growth hormone-releasing hormone (GHRH) consisting of all 44 amino acids of the native hormone with the addition of a trans-3-hexenoic acid group to the tyrosine at position 1. This modification enhances stability and receptor binding characteristics, making tesamorelin a valuable research tool for investigating the full-length GHRH signaling pathway with improved pharmacokinetic properties compared to native GHRH.
Published Research
Tesamorelin has been studied in peer-reviewed research across multiple areas:
- Full-length GHRH receptor activation and pituitary somatotroph signaling
- Growth hormone secretion dynamics and GH pulsatility pattern research
- Visceral adipose tissue metabolism and lipid distribution studies in animal models
- IGF-1 axis regulation and hepatic IGF-1 production research
- Comparative potency studies against native GHRH and truncated analogs (e.g., sermorelin)
- Lipid metabolism biomarkers including triglyceride and cholesterol panel modulation
- Cognitive biomarker research and neuroprotective pathway studies
Specifications
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Molecular Weight: 5135.89 g/mol
- Solubility: Soluble in bacteriostatic water or sterile water
- Storage: Store at -20°C for long-term stability. Reconstituted solutions should be refrigerated at 2–8°C
- CAS Number: 218949-48-5
Handling
This product is intended for laboratory research only. Reconstitute with bacteriostatic water for research applications. Use aseptic technique during preparation. Refer to published literature for appropriate research concentrations.
For research and laboratory use only. Not for human consumption. Sold exclusively to qualified researchers and licensed institutions.
