Description
Overview
TB-500 is a research-grade synthetic peptide corresponding to the active region of thymosin beta-4 (Tβ4), a 43-amino acid naturally occurring protein found in virtually all tissue and cell types. The active fragment centers on the actin-binding domain (amino acids 17–23), which is responsible for many of thymosin beta-4’s observed biological activities in research settings. TB-500 is widely utilized in preclinical research as a more practical and targeted research tool compared to the full-length protein.
Published Research
TB-500 and its parent compound thymosin beta-4 have been studied extensively, with key research areas including:
- Actin polymerization and cytoskeletal dynamics in cell migration studies
- Angiogenesis and new blood vessel formation in preclinical wound models
- Anti-inflammatory signaling pathways and cytokine modulation
- Cardiac tissue research and post-injury remodeling in animal models
- Dermal fibroblast proliferation and extracellular matrix protein regulation
- Hair follicle stem cell activation and differentiation studies
Specifications
- Purity: ≥99% (HPLC verified)
- Form: Lyophilized powder
- Molecular Weight: 4963 g/mol
- Solubility: Soluble in bacteriostatic water or sterile water
- Storage: Store at -20°C for long-term stability. Reconstituted solutions should be refrigerated at 2–8°C
- CAS Number: 77591-33-4
Handling
This product is intended for laboratory research only. Reconstitute with bacteriostatic water for research applications. Use aseptic technique during preparation. Refer to published literature for appropriate research concentrations.
For research and laboratory use only. Not for human consumption. Sold exclusively to qualified researchers and licensed institutions.
